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Unit 2 - Genetics
The technique used to test for genetic disorders is embryo screening.

Unit 2 - Genetics

This GCSE Biology quiz is all about genetics, the study of variation and inheritance. Genetics can also mean the genetic properties, characteristics or features of an organism. The rules of genetics were first worked out by Gregor Mendel in 1866 from studies of pea plants. He discovered that genetic particles (heredity units), which we now call genes, determine the features of the offspring. Later, with the discovery of DNA, we began to understand genetics much better.

Different versions of the same gene found on a pair of chromosomes in the nucleus of a cell are called alleles. These can determine features such as eye colour. Mendel recognised that there were dominant and recessive forms of these alleles. He also realised that genes are passed on from both parents and that recombination of genes during fertilisation is a random event. This means that every person on the Earth (other than identical twins who came from the same egg cell) has a unique set of genes. This can be analysed to provide a genetic fingerprint which looks a bit like a bar code!

1 .
What are alleles?
Different forms of an organism
Different forms of an animal
Different forms of a gene
Different forms of an enzyme
Alleles are given letters. A different letter of the alphabet is used for each gene. The dominant allele is given an upper case letter e.g. T and the recessive allele is given a lower case letter e.g. t
2 .
What is a carrier?
A person who has the disease and always passes it on to their offspring
A person who is unaffected by the disease but can pass on the gene
A person unaffected and incapable of passing on the condition through their genes
A person infected who can spread the disease through a droplet infection
This most commonly occurs with recessive conditions
3 .
What offspring ratio would you expect from two parents who are carriers - Tt crossed with Tt?
2:1
3:1
4:1
1:1
Only the offspring that receive the recessive genes from both parents will be unaffected by Huntington's disease
4 .
In humans, genes are found in...
pairs
threes
singly
fours
Genes are always found in pairs. One of the pair was inherited from Mum and the other one of the pair of genes comes from Dad
5 .
For a condition such as Huntington's disease, how many parents need to be affected for the children to inherit this condition?
One
Two
None
Only the grandparents
Huntington's disease is a dominant condition so only one copy of the faulty gene is needed to cause it. Normally, it is only diagnosed in middle-aged people, which means that they have already passed it on to their children. There is a form that affects children but it is very rare
6 .
What is the name of the technique used to test a foetus for genetic disorders?
Embryo screening
IVF
Cloning
Stem cells
Genetic tests are not available for all inherited diseases and sometimes they can give a false positive result
7 .
In a recessive condition, such as cystic fibrosis, how many copies of the abnormal allele are needed for the person to be a sufferer?
One
Three
Two
Four
Both parents need to be carriers for the child to inherit cystic fibrosis. Parents would be Cc and the child with cystic fibrosis would be cc
8 .
Humans have two sex chromosomes. What are the ones in women known as?
XY
X0
XX
XXY
Chromosomes occur in pairs. Men have an XY chromosome combination
9 .
If the genes were Tt, this means that the alleles are...
the same
identical
different
increased
You can tell that by the fact that there is a capital letter and also a small letter - genetics are case sensitive!
10 .
Sperm cells carry which of the following chromosomes?
Just an X chromosome
Just a Y chromosome
Neither X nor Y chromosomes
Either X or Y chromosomes
The egg cell contains only the X chromosome so it is the sperm that determines the gender of the offspring
You can find more about this topic by visiting BBC Bitesize - Genetics

Author:  Donna Maria Davidson

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